with Giles Yeo
Professor of Molecular Neuroendocrinology, University of Cambridge
Cambridge Weight Loss Scientist: Your Brain Fights Weight Loss! How To Keep It Off | Prof - Giles Yeo
Cambridge professor Giles Yeo reveals why your brain resists weight loss, how GLP-1 drugs work, and his 16:30:5 framework for sustainable eating.
Cambridge Weight Loss Scientist: Your Brain Fights Weight Loss! How To Keep It Off | Prof - Giles Yeo
with Giles Yeo
Professor of Molecular Neuroendocrinology, University of Cambridge
Cambridge professor Giles Yeo reveals why your brain resists weight loss, how GLP-1 drugs work, and his 16:30:5 framework for sustainable eating.
What this conversation is about
Cambridge professor Giles Yeo reveals why your brain resists weight loss, how GLP-1 drugs work, and his 16:30:5 framework for sustainable eating.
A Fellow of the Academy of Medical Sciences, Professor Giles Yeo MBE has spent 30 years at the University of Cambridge studying why some people feel hungrier, gain weight more easily, and find it harder to keep weight off than others. His research focuses on how genes, hormones, and the brain control appetite and body weight.
Key Takeaways
Your brain actively fights weight loss by increasing hunger and changing your metabolism.
Two people eating identical food can experience completely different levels of appetite and fullness.
Calories fail to capture how protein, fibre, and ultra-processed foods affect your body differently.
The 16:30:5 framework helps you eat enough protein and fibre while reducing free sugar.
Weight often returns after stopping GLP-1 drugs because the underlying biology remains unchanged.
Planning nutrition weekly rather than daily removes the pressure of perfecting every single meal.
Chapter Guide
Cambridge Weight Loss Scientist: Your Brain Fights Weight Loss! How To Keep It Off | Prof - Giles Yeo
31 chapters · 1:36:13
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Giles Yeo
A Fellow of the Academy of Medical Sciences, Professor Giles Yeo MBE has spent 30 years at the University of Cambridge studying why some people feel hungrier, gain weight more easily, and find it harder to keep weight off than others. His research focuses on how genes, hormones, and the brain control appetite and body weight.
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